Individual skill
setup-apnovo-remote-tool
Set up, launch, validate, and troubleshoot the AlphaProtein Novo (de novo enzyme design) ToolUniverse remote tool. Use when deploying or auditing this implementation.
skills/setup-apnovo-remote-tool/SKILL.md
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- Last checked
- Nov 9, 2026
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- Apache-2.0
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# Set up AlphaProtein Novo as a remote tool
> Validation status (2026-10-16): **`verified`.** The acceptance suite has now run twice, 12/12 requests answered each time with `peak_reserved_gib` 2.0 on every one; see `provider.toml`'s `verified_on`. Earlier status (2026-10-06): all five setup steps pass. On the NVIDIA GB10 (aarch64, cc 12.1, driver 580.173.02): `tu remote setup apnovo` reports preflight OK, environment present, kit at the pinned commit, weights 1/1 at their pins, and `smoke: OK — one prediction in 69s, peak reserved 2.0 GiB`, which agrees with the manifest's independently measured budget. The weights refusal was tested in both directions. Residency is **5.3x** at the published 1000 denoising steps (193.1 s for the design that pays the XLA compile, 36.6 s for the one that reuses it) and far larger at 50 steps (158.5 s and 1.99 s), where compilation rather than compute dominates — plan with the figure at your own step count. Folding and resequencing are deliberately not part of this provider. What has been established on
> the NVIDIA GB10 (aarch64, cc 12.1, driver 580.173.02) is the environment and
> the no-weights path: the 72-package lock installs natively, `alphafold3`'s C++
> extension builds from source, the pinned stack reports
> `jax.default_backend() == "gpu"` on `CudaDevice(id=0)` "NVIDIA GB10"
> cc 12.1, and a design manifest validates and its motif spec parses with no
> weights and no GPU. The generator weights have been fetched and their sha256
> recorded. **Not** established: the residency gain, the acceptance suite, and
> scientific quality. Folding and resequencing are deliberately not part of this
> provider — see the provider README for why. Keep this deployment private.
**Read `src/tooluniverse/remote/apnovo/README.md` before deploying.** This