Individual skill
tooluniverse-gwas-drug-discovery
Transform GWAS signals into drug targets and repurposing opportunities. Connects GWAS-significant loci to causal genes via fine-mapping/eQTL, then to druggable proteins via DGIdb/OpenTargets, then to existing drugs via ChEMBL. Use for GWAS-to-target hypothesis generation, druggable-fraction analysis of disease loci, and human-genetics-validated drug-repurposing prioritization.
plugin/skills/tooluniverse-gwas-drug-discovery/SKILL.md
Source commit 5598a9fc97e32964fe9b703818e7d0747142f179
What was checked
- Matches the observed repository HEAD
- Yes
- Scanner rules are current
- Yes
- Repository scan complete
- No
- Skill scan complete
- No
- Observed behavior
- Network or broad shell
- Last checked
- Nov 9, 2026
These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.
Install this skill
Choose an agent in your Stack or copy a command below. Commands fetch the pinned commit and copy only this skill directory. Existing destinations are refused. Copying a command does not install anything.
An install command is unavailable: current rules, complete repository and skill scans, an eligible behavior level and a permitted license are required.
Repository context
- Repository stars (not skill ratings)
- 1,779
- Repository last updated
- Nov 8, 2026
- License
- Apache-2.0
Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.
- agents Repository topic
- reasoning-agent Repository topic
- reasoning-language-models Repository topic
- tool-use Repository topic
- ai-agents Repository topic
- ai-scientists Repository topic
- automated-science Repository topic
- co-pilot Repository topic
- co-scientist Repository topic
- ai-for-science Repository topic
- engineering Derived category
Files and excerpt
File metadata and permitted, redacted excerpts come from the recorded scan. Source links are pinned to that commit.
Browse files
EXAMPLES.mddoc · 2,119 bytesPROCEDURES.mddoc · 4,980 bytesQUICK_START.mddoc · 29,995 bytesREFERENCE.mddoc · 6,265 bytesREPORT_TEMPLATE.mddoc · 2,548 bytesSKILL.mdcore · 10,428 bytesSKILL.mdcore · 10,428 bytespython_implementation.pyruns · 14,635 bytes
Read excerpt
# GWAS-to-Drug Target Discovery
Transform genome-wide association studies (GWAS) into actionable drug targets and repurposing opportunities.
**IMPORTANT**: Always use English terms in tool calls. Respond in the user's language.
---
## Overview
This skill bridges genetic discoveries from GWAS with drug development by:
1. **Identifying genetic risk factors** - Finding genes associated with diseases
2. **Assessing druggability** - Evaluating which genes can be targeted by drugs