Individual skill

setup-ef2inv-remote-tool

Set up, launch, validate, and troubleshoot the ESMFold2-binder-design ToolUniverse remote tool and optionally relay it through ToolUniverse Connect. Use when deploying or auditing this implementation.

skills/setup-ef2inv-remote-tool/SKILL.md

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# Set up ESMFold2 binder design as a remote tool

> Validation status (2026-10-01): the ESM cookbook's gradient-guided binder design ran on the NVIDIA GB10 (aarch64, cc 12.1) under the optimization kit's `fast` mode. **This is the only provider here that runs BACKWARD passes**, so the acceptance question is not only whether a graph replay survives a repeat but whether autograd state accumulates across requests. It does not: four consecutive identical requests in one held worker moved the high-water mark by 0.04 GiB, at 15.7 s then 5.1 s each. Peak reserved 28.03 GiB for the 135-token warm pass. **No VRAM ladder is declared, deliberately**: under `fast` the kit's checkpointing planner budgets 0.90x the card's total memory and grows to fill whatever card it is on above roughly 500 tokens, so a ladder would measure the host rather than the model. `shareable = false` says the same thing in the field a scheduler reads, and the bounded alternative is the kit's `big` mode rather than a knob. Public publication, cross-user isolation, concurrency, recovery and design quality are untested; keep this deployment private.

## Prerequisites

- Run from the ToolUniverse repository root on Linux with Python 3.12.3.
- A CUDA GPU is required. This provider holds its model resident between requests; CPU is not a target.
- Keep provider data, weights, caches, and credentials outside Git.
- Bind to loopback. A non-loopback bind requires TOOLUNIVERSE_API_TOKEN; never put it in arguments or results.

Run the standard-library contract check before downloading large dependencies:

~~~bash
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