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clinicaltrials-api

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Clinical trial registry database search API

skills/domains/biomedical/clinicaltrials-api/SKILL.md

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# ClinicalTrials API Guide

## Overview

ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies conducted around the world, maintained by the U.S. National Library of Medicine (NLM) at the National Institutes of Health (NIH). It contains registration records for over 500,000 clinical trials from more than 220 countries, making it the largest and most comprehensive clinical trial registry in the world.

The ClinicalTrials.gov API provides programmatic access to this vast repository of clinical trial data. Researchers can search for trials by condition, intervention, sponsor, location, phase, status, and many other criteria. The API returns detailed structured data including study design, eligibility criteria, outcome measures, enrollment information, study contacts, and results when available.

Clinical researchers, pharmaceutical companies, systematic reviewers, epidemiologists, public health officials, patient advocacy groups, and health policy analysts use the ClinicalTrials.gov API to monitor the clinical trial landscape, identify recruiting studies, conduct meta-analyses, analyze research trends, and ensure comprehensive evidence coverage in systematic reviews. The database is a critical resource for evidence-based medicine and regulatory compliance.

## Authentication

No authentication required. The ClinicalTrials.gov API is freely accessible without any API key, token, or registration. All endpoints are publicly available. Users are expected to comply with the NCBI usage policies and make requests at a reasonable rate.
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