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clinical-pharmacology-guide
Clinical pharmacology principles for dosing, drug interactions, and patient s...
skills/domains/pharma/clinical-pharmacology-guide/SKILL.md
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# Clinical Pharmacology Guide
A skill for applying clinical pharmacology principles to research and practice. Covers pharmacokinetic/pharmacodynamic modeling, drug interaction assessment, therapeutic drug monitoring, and special population dosing.
## Pharmacokinetic-Pharmacodynamic (PK/PD) Relationships
### The Emax Model
The most widely used PK/PD model relates drug concentration to effect:
```python
import numpy as np
import matplotlib.pyplot as plt
