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ncbi-blast-api

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Run sequence similarity searches via the NCBI BLAST REST API

skills/domains/biomedical/ncbi-blast-api/SKILL.md

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# NCBI BLAST REST API

## Overview

BLAST (Basic Local Alignment Search Tool) is the most widely used bioinformatics tool, comparing nucleotide or protein sequences against databases to find regions of similarity. The NCBI BLAST REST API enables programmatic submission of searches, status polling, and result retrieval. Free, no authentication required (but rate-limited).

## API Workflow

BLAST searches are asynchronous: submit → poll → retrieve.

### Step 1: Submit Search

```bash
# Nucleotide BLAST (blastn)
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