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pdb-structure-api

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Search and retrieve 3D protein structures from the RCSB Protein Data Bank

skills/domains/biomedical/pdb-structure-api/SKILL.md

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# RCSB Protein Data Bank API Guide

## Overview

The RCSB Protein Data Bank (PDB) is the single global archive for experimentally determined 3D structures of biological macromolecules. It hosts over 200,000 structures resolved by X-ray crystallography, cryo-EM, NMR spectroscopy, and other methods. Each entry includes atomic coordinates, experimental metadata, polymer sequences, bound ligands, and literature references.

Two complementary APIs are available. The **Data API** (`data.rcsb.org`) serves structured entry metadata, polymer entities, and chemical components via RESTful GET endpoints. The **Search API** (`search.rcsb.org`) supports full-text, attribute-based, sequence similarity, and structure similarity searches.

## Authentication

No authentication required. Both APIs are freely accessible without API keys, tokens, or registration.

## Core Endpoints
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