Individual skill
tooluniverse-adverse-outcome-pathway
Map environmental and industrial chemicals to adverse outcome pathways (AOPs) — molecular initiating event to organ-level toxicity. Uses AOPWiki, GHS classification, IARC carcinogen status, and LD50 data. Use for environmental/industrial chemical risk assessment, regulatory-grade hazard characterization, and AOP stressor mapping. Distinct from drug-safety analysis (use tooluniverse-pharmacovigilance for drugs).
skills/tooluniverse-adverse-outcome-pathway/SKILL.md
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- Last checked
- Nov 5, 2026
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- Repository last updated
- Nov 7, 2026
- License
- Apache-2.0
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# Adverse Outcome Pathway & Regulatory Risk Assessment
Distinct from drug safety (see tooluniverse-toxicology): this skill targets **environmental and
industrial chemicals** where the focus is AOP stressor mapping, GHS classification, LD50 hazard
quantification, and IARC carcinogen status — not FAERS signals or FDA drug labels.
## When to Use
Apply when researcher asks about:
- "What AOPs are associated with [pesticide/solvent/industrial chemical]?"
- "What is the GHS hazard classification for [compound]?"
- "What is the LD50 for [compound]?"
- "Is [compound] a carcinogen (IARC classification)?"
- "Which genes does [chemical] interact with (CTD)?"