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gtex-database
Query GTEx (Genotype-Tissue Expression) portal for tissue-specific gene expression, eQTLs (expression quantitative trait loci), and sQTLs. Essential for linking GWAS variants to gene regulation, understanding tissue-specific expression, and interpreting non-coding variant effects.
skills/12-科学数据库/gtex-database/SKILL.md
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# GTEx Database
## Overview
The Genotype-Tissue Expression (GTEx) project provides a comprehensive resource for studying tissue-specific gene expression and genetic regulation across 54 non-diseased human tissues from nearly 1,000 individuals. GTEx v10 (the latest release) enables researchers to understand how genetic variants regulate gene expression (eQTLs) and splicing (sQTLs) in a tissue-specific manner, which is critical for interpreting GWAS loci and identifying regulatory mechanisms.
**Key resources:**
- GTEx Portal: https://gtexportal.org/
- GTEx API v2: https://gtexportal.org/api/v2/
- Data downloads: https://gtexportal.org/home/downloads/adult-gtex/
- Documentation: https://gtexportal.org/home/documentationPage
## When to Use This Skill
