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cobrapy

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Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

skills/10-材料科学与物理计算/cobrapy/SKILL.md

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# COBRApy - Constraint-Based Reconstruction and Analysis

## Overview

COBRApy is a Python library for constraint-based reconstruction and analysis (COBRA) of metabolic models, essential for systems biology research. Work with genome-scale metabolic models, perform computational simulations of cellular metabolism, conduct metabolic engineering analyses, and predict phenotypic behaviors.

## Core Capabilities

COBRApy provides comprehensive tools organized into several key areas:

### 1. Model Management

Load existing models from repositories or files:
```python
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