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jaspar-database

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    # JASPAR Database Skill - Complete Content

**Name:** jaspar-database

**Description:** "Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation."

**License:** CC0-1.0

**Skill Author:** Kuan-lin Huang

## Overview

JASPAR (https://jaspar.elixir.no/) serves as the authoritative open-access repository of curated transcription factor binding profiles represented as position frequency matrices. The 2024 version contains approximately 1,210 non-redundant profiles across 164 eukaryotic species, with each profile derived from experimental validation methods.

## Core Capabilities
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