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boltz

Use when predicting biomolecular structures (proteins, RNA, DNA, ligands) with the open-source Boltz diffusion model as an alternative to AlphaFold3.

skills/boltz/SKILL.md

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# Boltz Structure Prediction

Predict biomolecular structures using Boltz, an open-source diffusion model. Boltz handles proteins, RNA, DNA, small molecules, ions, and covalent modifications in a single model without requiring multiple sequence alignments (MSA-optional). It serves as a strong open-source alternative to AlphaFold3.

## Requirements

- Python 3.10+
- 24 GB GPU VRAM minimum (A10G/A100 recommended)
- ~10 GB disk for model weights

## Installation

```bash
pip install boltz