Individual skill
folklore-variant-evidence
Retrieves ClinGen gene-disease validity assertions for a public gene or disease, and reviews source-linked public evidence and literature for one supported GRCh38 germline nuclear SNV or simple indel through Folklore Clinical Variant Interpretation MCP. Used when a scientific agent must branch deterministically on resolved, ambiguous, not-found, invalid, unsupported, or unavailable variant outcomes; chain a resolved public variant into related literature or publication details; or preserve evidence provenance without accepting patient, phenotype, family, segregation, or private case data.
skills/folklore-variant-evidence/SKILL.md
Source commit 2d2065fb4520fa3f3f2bcf61cff26ec8b7eba4b5
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- Observed behavior
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- Last checked
- Nov 10, 2026
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- 56,792
- Repository last updated
- Nov 9, 2026
- License
- MIT
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- ai-scientist Repository topic
- bioinformatics Repository topic
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- clinical-research Repository topic
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# Folklore Variant Evidence
Use Folklore Clinical Variant Interpretation MCP to retrieve structured public
variant evidence, automated variant-level ACMG/AMP decision support, provenance,
and source-linked literature for professional review. Keep the workflow limited
to public identifiers and preserve every explicit outcome state. Adapter 1.5.0 also provides ClinGen Gene-Disease Validity assertions; source coverage is bounded, not every known association.
Folklore Clinical Variant Interpretation MCP is published by Helena
Bioinformatics. Its hosted endpoint is:
```text
https://api.helena.bio/folklore/v1/mcp
```
