Individual skill
cobrapy
Performs constraint-based metabolic modeling with COBRApy, including FBA, pFBA, FVA, gene knockouts, flux sampling, growth media, production envelopes, gap filling, and SBML model validation for systems biology and metabolic engineering.
skills/cobrapy/SKILL.md
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# COBRApy - Constraint-Based Reconstruction and Analysis
## When to use
Use for loading/building metabolic networks, optimizing their steady-state fluxes,
knockout screens, medium design, feasible-space sampling, and gap-filling hypotheses.
FBA is a constraint-based prediction; it does not infer kinetic rates or establish
experimental growth, thermodynamic feasibility, or flux identifiability.
## Setup and reproducibility
Targets **cobra 0.32.1** (import `cobra`), checked against its released source and
[current documentation](https://cobrapy.readthedocs.io/en/latest/).
