Individual skill

primekg

Queries a pinned Precision Medicine Knowledge Graph (PrimeKG) CSV for typed gene, drug, disease, and phenotype nodes, direct associations, disease context, and one- or two-hop paths. Use for PrimeKG reproducibility, biological association lookup, and hypothesis generation with relation and data provenance preserved.

skills/primekg/SKILL.md

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Nov 9, 2026
License
MIT

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# PrimeKG Knowledge Graph

## When to use

Use for reproducing PrimeKG analyses, resolving entities in a specific graph artifact,
or exploring recorded gene, drug, disease, phenotype, anatomy, and pathway associations.
A path supports a research hypothesis; it does not establish causality, treatment efficacy,
a prescribing recommendation, or a diagnostic conclusion.

[PrimeKG upstream](https://github.com/mims-harvard/PrimeKG) now recommends OptimusKG for
new work. This skill remains scoped to PrimeKG CSVs; the helper is not an OptimusKG client.
Published PrimeKG integrates 20 resources, with approximately 129,000 nodes and
4.05 million undirected relationships. CSVs contain reverse rows, so row counts differ
from distinct undirected relationship counts. Count the actual pinned artifact.
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