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jaspar-database

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Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs, resolving gene symbols to JASPAR Matrix IDs, or getting TF metadata. Supports multiple output formats (MEME, TRANSFAC, PFM, JASPAR, YAML).

skills/jaspar_database/SKILL.md

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# JASPAR Skill

JASPAR is the definitive open-access database for Transcription Factor (TF)
binding profiles, stored as Position Frequency Matrices (PFMs).

Use this skill to map abstract sequence motifs or genomic regions to specific
biological regulators (e.g., "what TFs bind here?" or "what is the motif for
CTCF?").

## Prerequisites

1.  **`uv`**: Read the `uv` skill and follow its Setup instructions to ensure
    `uv` is installed and on PATH.
2.  **User Notification**: If .licenses/jaspar_database_LICENSE.txt does not