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scanpy

Single-cell RNA-seq and retained scverse workflow owner. Load .h5ad/10X data, manage AnnData metadata, plan scVI/scANVI batch-correction workflows, QC, normalization, PCA/UMAP/t-SNE, Leiden clustering, marker genes, cell type annotation, trajectory, for scRNA-seq analysis.

bundled/skills/scanpy/SKILL.md

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# Scanpy: Single-Cell Analysis

## Overview

Scanpy is a scalable Python toolkit for analyzing single-cell RNA-seq data, built on AnnData. Apply this skill for complete single-cell workflows including quality control, normalization, dimensionality reduction, clustering, marker gene identification, visualization, and trajectory analysis.

In the bundled Vibe-Skills routing surface, this skill also absorbs the former AnnData and scVI/scANVI route surfaces. Use it for h5ad container handling and scverse latent-model planning when those tasks appear inside a single-cell workflow.

## When to Use This Skill

This skill should be used when:
- Analyzing single-cell RNA-seq data (.h5ad, 10X, CSV formats)
- Performing quality control on scRNA-seq datasets
- Creating UMAP, t-SNE, or PCA visualizations
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