Individual skill

ld-1000g-region-compute

Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant. Single client (on-demand region fetch from EBI 1000G FTP); no multi-GB cold-start.

skills/ld-1000g-region-compute/SKILL.md

Source commit df61706c3e32fea21ad88f5b8a5189c895f9524d

What was checked

Matches the observed repository HEAD

Yes

Scanner rules are current

Yes

Repository scan complete

No

Skill scan complete

No

Observed behavior

Network or broad shell

Last checked

Nov 10, 2026

These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.

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