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jama-neurology

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Use when targeting JAMA Neurology or deciding whether a clinical-neurology study fits this venue. Encodes the journal's fit, the neurological-trial and observational evidence bar, reporting-guideline and trial-registration requirements, JAMA Network house style, official-submission re-check, and desk-reject heuristics. Venue-fit aid only, not clinical advice.

Clinical-Medicine-Journal-Skills/skills/jama-neurology/SKILL.md

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Sep 27, 2026
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# JAMA Neurology (jama-neurology)

## Journal positioning

JAMA Neurology is a JAMA Network specialty journal for clinical neurology research
across the breadth of neurological disease — neurodegenerative, cerebrovascular,
neuroimmune, epilepsy, movement, neuromuscular, and headache disorders. It favors
randomized clinical trials and rigorous observational and biomarker studies tied to
clinically meaningful neurological outcomes, with JAMA's emphasis on adequate power,
validated endpoints, and direct relevance to neurological practice. Mechanistic
bench neuroscience, small case series, and biomarker correlations without clinical
endpoints are a weak fit; that work belongs to a translational-neuroscience venue.
This skill is a **fit / venue-selection / re-framing** aid; it is not clinical or
regulatory advice and does not replace the journal's current instructions for authors.
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