Individual skill
lancet-statistics
Use to enforce The Lancet's clinical-statistics reporting — confidence intervals over bare P values, a pre-specified primary analysis, intention-to-treat with per-protocol sensitivity, multiplicity control for secondary endpoints, cautious pre-specified subgroup analyses with interaction tests, missing-data handling, and absolute plus relative effects.
Lancet-Skills/skills/lancet-statistics/SKILL.md
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# Clinical Statistics (lancet-statistics)
## When to trigger
- Results report P values but not confidence intervals or effect sizes.
- The primary analysis population (ITT vs per-protocol) is unclear.
- Many secondary endpoints or subgroups are reported with no multiplicity/interaction handling.
- A **statistical reviewer** is likely (The Lancet uses them) and the analysis is not pre-specified.
## The reporting backbone (every clinical estimate)
Each estimate needs: **effect measure + 95% CI + the analysis population + the pre-specified test.**
- [ ] **Confidence intervals** for every key estimate — CIs over bare P values; The Lancet de-emphasises isolated significance.