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nejm

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Use when targeting The New England Journal of Medicine (NEJM) or deciding whether a clinical medicine manuscript fits this venue. Encodes the journal's fit, framing, practice-changing evidence bar, CONSORT/registration requirements, house style, official-submission re-check, and desk-reject heuristics.

English-NaturalScience-Journal-Skills/skills/nejm/SKILL.md

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# The New England Journal of Medicine (nejm)

## Journal positioning

The New England Journal of Medicine, published by the Massachusetts Medical Society, is the most widely read and cited general medical journal in the world. It publishes clinical trials, epidemiological studies, and clinical reviews that change or define standard-of-care practice across all of medicine. The NEJM editorial culture is centered on clinical practice impact: a study must be definitive, practice-changing, and broadly relevant to physicians across specialties — not merely statistically significant or methodologically rigorous in the abstract. The readership is the global physician and clinical-researcher community; non-clinicians are a secondary audience. This skill is a **fit / venue-selection / re-framing** tool. It does not replace the journal's current official submission guidelines. Before submitting, re-check the live author instructions on nejm.org.

## When to trigger

- The author names NEJM or The New England Journal of Medicine as the target venue.
- A randomized controlled trial, definitive epidemiological study, or landmark diagnostic-accuracy study has clear practice-changing implications across medicine.
- A clinical research team needs to calibrate whether their study meets the NEJM significance bar or should route to The Lancet, JAMA, or a specialty journal.
- The author needs NEJM's specific format requirements (structured abstract, CONSORT, registration) and desk-reject risks before submitting.

## Scope & topic fit
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