Individual skill

molcell-rebuttal

Use after Molecular Cell reviews arrive to triage the decision, prioritize the (often mechanism-completing) new experiments by impact × feasibility, and draft a point-by-point response that is respectful, evidence-led, and closes the mechanistic gaps reviewers demand. Do not run before the experiments and revision are actually done.

Molecular-Cell-Skills/skills/molcell-rebuttal/SKILL.md

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# Reviewer Rebuttal (molcell-rebuttal)

## When to trigger

- A decision letter arrives (reject / reject-but-resubmit / major or minor revision).
- You have reviewer comments and need a strategy before running experiments.
- A revision is drafted and you need the point-by-point response letter.

## What's distinctive about Molecular Cell reviews

Molecular Cell reviewers are usually **molecular specialists** who probe the mechanism hard. The recurring theme is not breadth but **mechanistic completeness and rigor**: they push for the molecular step to be nailed down, alternatives excluded with separation-of-function experiments, and in-vitro claims validated in cells. Expect requests for **point mutants, reconstitutions, orthogonal biochemistry, or an additional structural/genomic control** — real bench work, not just rewriting.

## Step 0: read the editor's letter first
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