Individual skill
cancer-discovery
Use when targeting Cancer Discovery (AACR) or deciding whether a cancer biology or translational oncology manuscript fits this venue. Encodes the journal's fit, framing, method-and-evidence bar, house style, official-submission re-check, and desk-reject heuristics.
English-NaturalScience-Journal-Skills/skills/cancer-discovery/SKILL.md
Source commit 932eb23331721b16e967c59f093781be1928b498
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- Last checked
- Nov 9, 2026
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- Repository last updated
- Sep 27, 2026
- License
- MIT
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# Cancer Discovery (cancer-discovery)
## Journal positioning
Cancer Discovery is the flagship research journal of the American Association for Cancer Research and the leading venue for high-impact cancer biology and translational oncology. Its editorial DNA is built around discoveries that fundamentally advance understanding of cancer biology and carry immediate translational implications: driver oncogenes, tumor suppressor mechanisms, clonal evolution, drug resistance, immune evasion, and precision oncology strategies — with human cancer data (tumor genomics, patient cohorts, clinical specimens, early-phase trial results) as either primary or strong corroborating evidence. Cancer Discovery occupies the tier above Cancer Cell (which accepts rigorous mechanism without a mandatory translational claim) and below Nature/Science for cancer-specific work; it is the AACR community's highest-priority outlet before submitting to broad-science venues.
This skill is a **fit / venue-selection / re-framing** tool. It does not replace the journal's current official submission guidelines. Before submitting, re-check the live author instructions on the AACR / Cancer Discovery platform.
## When to trigger
- The author names Cancer Discovery or the AACR flagship as the target venue.
- A cancer biology study needs venue selection among Cancer Discovery, Cancer Cell, and Nature Medicine.
- A translational oncology paper with tumor genomics and a clinical component needs framing guidance.
- The author needs Cancer Discovery's specific desk-reject risks and a ranked alternative list before submitting.