Individual skill
cell-stem-cell
Use when targeting Cell Stem Cell or deciding whether a stem-cell or regenerative-biology manuscript fits this Cell Press venue. Encodes the journal's fit, framing, method-and-evidence bar, house style, official-submission re-check, and desk-reject heuristics.
English-NaturalScience-Journal-Skills/skills/cell-stem-cell/SKILL.md
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- Last checked
- Nov 9, 2026
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# Cell Stem Cell (cell-stem-cell)
## Journal positioning
Cell Stem Cell is the Cell Press flagship for stem-cell biology, regenerative medicine, and reprogramming. It publishes mechanistic studies in which stem or progenitor cells are the central biological unit — from pluripotency regulation and lineage specification through tissue-specific adult stem cells, organoids, and cellular reprogramming. The journal bridges fundamental developmental and cell biology with translational and therapeutic applications, but it demands mechanistic depth throughout: a paper that is primarily clinical or descriptive, without a molecular or cellular mechanism, does not fit. The readership spans developmental biologists, cell biologists, geneticists, and regenerative-medicine researchers; the advance must be legible and significant to this combined audience.
This skill is a **fit / venue-selection / re-framing** tool. It does not replace the journal's current official submission guidelines. Before submitting, re-check the live author instructions on the Cell Press site.
## When to trigger
- The author names Cell Stem Cell as the target venue.
- A paper in stem-cell biology, reprogramming, or organoid biology needs the Cell Press flagship in the field.
- A mechanistic study of cell fate, lineage commitment, or tissue regeneration has both molecular depth and in vivo relevance and the author is choosing between Cell Stem Cell, `cell`, and `developmental-cell`.
- The author needs Cell Stem Cell's specific evidence bar (mechanism + in vivo requirement), STAR Methods obligations, and desk-reject patterns before submitting.