Individual skill

cell-host-and-microbe

Use when targeting Cell Host & Microbe (Cell Host Microbe) or deciding whether a host-microbe interaction or microbiome manuscript fits this venue. Encodes the journal's fit, framing, method-and-evidence bar, house style, official-submission re-check, and desk-reject heuristics.

English-NaturalScience-Journal-Skills/skills/cell-host-and-microbe/SKILL.md

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Last checked
Nov 9, 2026

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Repository last updated
Sep 27, 2026
License
MIT

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# Cell Host & Microbe (cell-host-and-microbe)

## Journal positioning

Cell Host & Microbe is the Cell Press flagship for host-pathogen interaction, microbiome biology, and the interface between microorganisms and multicellular hosts across kingdoms. It publishes mechanistic discoveries that redefine how host and microbe co-opt, tolerate, or resist each other — from viral entry and bacterial pathogenesis to commensal regulation of immunity and metabolism. The readership spans microbiology, immunology, virology, and translational medicine, so a paper must advance understanding beyond its specific pathogen or microbial community. This skill is a **fit / venue-selection / re-framing** tool. It does not replace the journal's current official submission guidelines. Before submitting, re-check the live author instructions on the Cell Press site and the submission system.

## When to trigger

- The author names Cell Host & Microbe or Cell Host Microbe as the target venue.
- A host-pathogen or microbiome study has clear mechanistic depth and broad significance extending beyond a single organism or single pathogen species.
- A manuscript frames infection or commensal biology in terms of cellular or molecular mechanism and needs re-positioning for Cell Press editorial culture.
- The author is choosing between Cell Host & Microbe and Immunity, Nature Immunology, or Nature Microbiology and needs the venue-specific significance calibration.
- The author needs Cell Host & Microbe's desk-reject risks and credible alternative-venue routing before submitting.
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