Individual skill

bioconductor-crisprscore

Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to

skills/transcriptomics/crisprscore/SKILL.md

Source commit c9bd4d8eb6edc5308a8f55e6184dce9e8afadf12

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Last checked

Nov 4, 2026

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