Individual skill

translational-research

Reason about translational research problems in HCLS — especially neurology and hypothesis validation. Use when the user asks to design a validation study, evaluate a target, qualify a biomarker, choose endpoints, critique a preclinical-to-clinical plan, pick a trial design (basket/umbrella/platform), plan multimodal data integration, or assess whether a hypothesis is ready to advance. Triggers include phrases like "validate target", "biomarker context of use", "bench to bedside", "T0/T1/T2/T3/T4", "proof of mechanism", "target engagement", "design a trial for", "preclinical model translates", "imaging-genetics", "is this ready for Phase 2", "mouse results to humans", "GWAS/eQTL/MR", "endpoint selection", "drug repurposing rationale", "fail fast".

skills/translational-research/SKILL.md

Source commit 4603541c396cdd845dbae554800a65132d12bb63

What was checked

Matches the observed repository HEAD

Yes

Scanner rules are current

No

Repository scan complete

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Skill scan complete

Yes

Observed behavior

Not checked yet

Last checked

Nov 11, 2026

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