Individual skill

calc-sample-size

Use when planning how many patients or cases a study needs before data collection (power analysis, IRB justification). Walks a decision tree to the right test and returns reproducible R/Python code and IRB-ready justification text. Analyzing collected data is /analyze-stats.

skills/calc-sample-size/SKILL.md

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# Calc-Sample-Size Skill

## Decision Tree

Walk the user through this tree one question at a time; do not assume answers. Reader studies,
segmentation and model-comparison designs sit outside the tree: see Tests 14–17.

```
What is your primary outcome?
|
+-- Binary (yes/no, positive/negative)
|   |
|   +-- Paired data (same subjects, two methods)?
|   |   +-- YES --> [5] McNemar test
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