Individual skill

indication-dossier

Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.

resources/skills/indication-dossier/SKILL.md

Read pinned source

Source commit 357d1a980056e191f380d0e01ec4fbc7cf529d1b

What was checked

Matches the observed repository HEAD: Yes
Scanner rules are current: Yes
Repository scan complete: No
Skill scan complete: Yes
Observed behavior: Network or broad shell
Last checked: Nov 9, 2026

These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.

Install this skill

Choose an agent in your Stack or copy a command below. Commands fetch the pinned commit and copy only this skill directory. Existing destinations are refused. Copying a command does not install anything.

An install command is unavailable: current rules, complete repository and skill scans, an eligible behavior level and a permitted license are required.

Repository context

Repository stars (not skill ratings): 5,501
Repository last updated: Nov 9, 2026
License: Apache-2.0

Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.

ai-for-science Repository topic
local-first Repository topic
reproducible-research Repository topic
open-science Repository topic
ai-research Repository topic
model-agnostic Repository topic
scientific-ai Repository topic
desktop-app Repository topic
ai-workbench Repository topic
open-source Repository topic
legal Derived category

Files and excerpt

File metadata and permitted, redacted excerpts come from the recorded scan. Source links are pinned to that commit.

Browse files

.catalog_stampasset · 13 bytes
SKILL.mdcore · 6,550 bytes
references/00-research-standards.mddoc · 3,101 bytes
references/01-meta-initialization.mddoc · 1,729 bytes
references/02-epidemiology-research.mddoc · 2,113 bytes
references/03-biology-soc-research.mddoc · 2,373 bytes
references/04-regulatory-trials-research.mddoc · 3,159 bytes
references/05-synthesis.mddoc · 5,340 bytes
references/06-writing-style.mddoc · 1,746 bytes
references/waypoint-schemas.mddoc · 2,954 bytes

Read excerpt


# Indication Dossier

Produces a structured research dossier on a single indication, framed as a
patient population: who they are, what's wrong, how they're treated today,
and how clinical trials can be designed to help them. Runs as five phases
that write resumable waypoint files; after a brief identity check at the end
of Phase 1, the remaining phases run straight through.

## Framing

**Think of an indication as a patient population.** Frame everything
from the patient perspective: "Who are these patients?" not "What is this
disease?"; "How are these patients identified and managed?" not "What causes
this condition?"; population nesting: "all patients in {child} are patients