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uniprot-database

Direct REST API access to UniProt for protein search, entry retrieval, and identifier mapping; use when you need programmatic UniProtKB queries or cross-database ID conversion.

scientific-skills/Evidence Insight/uniprot-database/SKILL.md

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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)

## When to Use

- You need to search UniProtKB with Lucene-style queries (e.g., by gene name, organism, reviewed status).
- You want to fetch the full details of a specific protein entry by UniProt accession (e.g., `P12345`).
- You need to map identifiers between databases (e.g., gene names, Ensembl IDs, RefSeq IDs ↔ UniProt accessions).
- You are building pipelines that require automated protein annotation retrieval in JSON/TSV/FASTA formats.
- You need a lightweight client that talks directly to UniProt’s REST API without additional SDKs.

## Key Features

- **Protein search** via UniProtKB REST endpoint using Lucene query syntax.
- **Entry retrieval** by accession with selectable output formats.
- **Identifier mapping** between supported source/target databases using UniProt ID mapping service.
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