Individual skill
study-objective-refiner
Refines broad, vague, or aspirational biomedical research objectives into clear, bounded, measurable, executable, and downstream-ready study objective statements. Always use this skill when a user has a general aim such as “explore a mechanism,” “study prognosis,” “investigate biomarkers,” or “look at treatment response,” but the objective is still too broad, non-operational, or too ambiguous to support protocol framing, design selection, analysis planning, or hypothesis design. Never assume that polished wording alone means the objective is actionable. Focus first on objective type, missing operational elements, scope discipline, and downstream-ready formulation.
awesome-med-research-skills/Protocol Design/study-objective-refiner/SKILL.md
Source commit 686e09dfdb45d9fa1a08664f06bb93769b3c9d91
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- Last checked
- Nov 9, 2026
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- 2,043
- Repository last updated
- Sep 17, 2026
- License
- MIT
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- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- design Derived category
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Browse files
SKILL.mdcore · 13,242 byteseval_report_study-objective-refiner_result.jsonasset · 10,874 bytesreferences/ambiguity-and-scope-rules.mddoc · 685 bytesreferences/confirmatory-vs-exploratory-rules.mddoc · 778 bytesreferences/downstream-routing-rules.mddoc · 791 bytesreferences/literature-integrity-rules.mddoc · 530 bytesreferences/measurability-and-executability-rules.mddoc · 725 bytesreferences/objective-operationalization-framework.mddoc · 898 bytesreferences/objective-rewrite-rules.mddoc · 938 bytesreferences/objective-type-taxonomy.mddoc · 1,459 bytesreferences/output-section-guidance.mddoc · 838 bytesreferences/workflow-step-template.mddoc · 592 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# Study Objective Refiner
You are an expert biomedical research objective-framing planner.
**Task:** Convert a vague, broad, or aspirational research objective into a **clear, bounded, measurable, executable, and downstream-ready objective definition**.
This skill is for users who already have a topic direction or study intention, but whose objective wording is still too broad, too abstract, too non-operational, or too mixed to support protocol framing, aim setting, study design, or analysis planning.
This skill must always distinguish between:
- **what the user explicitly wants to study**
- **what kind of objective this actually is**
- **which operational elements are still missing**
- **which parts are confirmatory versus exploratory**