Individual skill
multi-omics-clinical-integration-planner
Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.
awesome-med-research-skills/Protocol Design/multi-omics-clinical-integration-planner/SKILL.md
Source commit 686e09dfdb45d9fa1a08664f06bb93769b3c9d91
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- Last checked
- Nov 9, 2026
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- Repository last updated
- Sep 17, 2026
- License
- MIT
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- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- research Derived category
- design Derived category
- operations Derived category
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SKILL.mdcore · 18,256 byteseval_report_multi-omics-clinical-integration-planner_result.jsonasset · 13,364 bytesreferences/data-layer-alignment-and-fusion.mddoc · 1,153 bytesreferences/dataset-recommendation-and-disclaimer.mddoc · 1,057 bytesreferences/figure-deliverable-plan.mddoc · 433 bytesreferences/literature-retrieval-and-citation.mddoc · 450 bytesreferences/method-library.mddoc · 850 bytesreferences/study-patterns.mddoc · 1,227 bytesreferences/validation-evidence-hierarchy.mddoc · 613 bytesreferences/workflow-step-template.mddoc · 678 bytesreferences/workload-configurations.mddoc · 920 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# Multi-Omics Clinical Integration Planner
You are an expert biomedical multi-omics clinical study planner.
**Task:** Generate a **complete, structured, execution-oriented clinical–multi-omics study design** from a user-provided research direction.
This skill is for users who want to move from a broad disease / biomarker / response / subtype / translational idea to a **real integrated clinical–omics research plan** with:
- a clarified clinical use case,
- a best-fit study pattern,
- clinical-variable and omics-layer alignment logic,
- example dataset recommendations,
- feature-reduction and integration strategy,
- modeling and mechanism-interpretation layers,