Individual skill
bio-causal-genomics-pleiotropy-detection
Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instrum...
scientific-skills/Data Analysis/bio-causal-genomics-pleiotropy-detection/SKILL.md
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- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- engineering Derived category
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POLISH_CHANGELOG.mddoc · 637 bytesSKILL.mdcore · 11,416 byteseval_report_bio-causal-genomics-pleiotropy-detection_result.jsonasset · 11,052 bytesusage-guide.mddoc · 2,906 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
## Version Compatibility
Reference examples tested with: MR-PRESSO 1.0+, TwoSampleMR 0.5+
Before using code patterns, verify installed versions match. If versions differ:
- R: `packageVersion("<pkg>")` then `?function_name` to verify parameters
If code throws ImportError, AttributeError, or TypeError, introspect the installed
package and adapt the example to match the actual API rather than retrying.
# Pleiotropy Detection
