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kegg-database

Direct access to KEGG via the REST API for academic-only pathway/gene/compound/drug queries; use when you need precise HTTP-level control or targeted KEGG ID mapping.

scientific-skills/Evidence Insight/kegg-database/SKILL.md

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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)

## When to Use

- You need to fetch **KEGG pathway, gene, compound, enzyme, disease, or drug** records directly from the **KEGG REST API**.
- You want to perform **gene ↔ pathway** mapping (e.g., building inputs for pathway enrichment or reporting).
- You need **cross-references** between KEGG databases (e.g., pathway → genes, gene → KO, pathway → compounds).
- You must **convert identifiers** between KEGG and external databases (e.g., KEGG gene → NCBI Gene ID / UniProt; KEGG compound → PubChem).
- You need **drug–drug interaction (DDI)** lookups for KEGG drug IDs.

> Note: KEGG REST access is intended for academic use. Non-academic/commercial use may require a separate KEGG license.

## Key Features

- Full coverage of core KEGG REST operations via Python helpers:
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