Individual skill
brenda-database
Programmatic access to the BRENDA enzyme database via the SOAP API; use when you need kinetic constants (Km, kcat, Vmax), reaction equations, enzyme properties (pH/temperature optima, stability), or enzyme discovery by EC/substrate/product.
scientific-skills/Evidence Insight/brenda-database/SKILL.md
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- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
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- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
## When to Use
- You need **kinetic parameters** (e.g., Km, kcat, Vmax) for a specific enzyme, organism, or EC number.
- You want **reaction equations/stoichiometry** associated with an enzyme (by EC number or enzyme name).
- You need **enzyme property data** such as optimal pH/temperature, stability, inhibitors, or activators.
- You want to **discover enzymes** by searching for a substrate, product, or EC number.
- You need to **automate retrieval** of BRENDA data in a Python pipeline (e.g., for modeling, annotation, or curation).
## Key Features
- SOAP-based programmatic access to the BRENDA database.
- Retrieval of:
- Kinetic data: Km, kcat, Vmax