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buffer-calculator

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Calculate precise buffer recipes with accurate mass and volume measurements for molecular biology and biochemistry. Supports PBS, RIPA, and TAE with concentration scaling, stock solution preparation, pH adjustment guidance, and step-by-step protocols.

scientific-skills/Other/buffer-calculator/SKILL.md

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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)

# Buffer Calculator

Calculate precise buffer formulations with accurate mass and volume measurements for molecular biology, biochemistry, and cell culture applications. Supports predefined common buffers and customizable calculations with pH adjustment guidance.

**Key Capabilities:**
- **Predefined Buffer Library**: PBS, RIPA, TAE with accurate molecular weights
- **Precise Mass Calculations**: Component masses to milligram precision
- **Volume-Based Components**: Handle liquid components (detergents, acids)
- **Concentration Scaling**: Scale from stock solutions (10X, 20X) to working concentrations
- **Step-by-Step Protocols**: Detailed preparation instructions with safety notes

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