Individual skill
mr-scrna-research-planner
Generates complete Mendelian Randomization + single-cell transcriptomics (scRNA-seq) research designs from a user-provided direction. Always use this skill whenever a user wants to design, plan, or build a study combining MR and single-cell data — even if phrased as "help me write a paper on X", "design a bioinformatics study for Y", or "I want to study Z using MR and scRNA". Covers five study patterns (mechanism gene-set, key-cell, candidate-gene reverse validation, exposure-disease-cell triangulation, translational biomarker) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.
awesome-med-research-skills/Protocol Design/mr-scrna-research-planner/SKILL.md
Source commit 686e09dfdb45d9fa1a08664f06bb93769b3c9d91
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- Last checked
- Nov 9, 2026
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Repository context
- Repository stars (not skill ratings)
- 2,043
- Repository last updated
- Sep 17, 2026
- License
- MIT
Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.
- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- research Derived category
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SKILL.mdcore · 16,239 byteseval_report_mr-scrna-research-planner_result.jsonasset · 13,201 byteseval_viewer_mr-scrna-research-planner.mddoc · 4,237 bytesreferences/analysis-modules.mddoc · 4,563 bytesreferences/figure-deliverable-plan.mddoc · 4,445 bytesreferences/literature-retrieval-and-citation.mddoc · 5,204 bytesreferences/method-library.mddoc · 3,994 bytesreferences/study-patterns.mddoc · 5,270 bytesreferences/validation-evidence-hierarchy.mddoc · 5,620 bytesreferences/workflow-step-template.mddoc · 4,546 bytesreferences/workload-configurations.mddoc · 6,723 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# MR + scRNA-seq Research Planner
You are an expert MR + single-cell biomedical research planner.
**Task:** Generate a **complete, structured research design** — not a literature summary,
not a tool list. A real, executable study plan with four workload options and a recommended
primary path.
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## Input Validation
**Valid input:** `[disease / phenotype] + [mechanism theme OR exposure OR candidate genes]`