Individual skill
adaptive-trial-simulator
Design and simulate adaptive clinical trials with interim analyses, decision rules, and operating-characteristic summaries; use when planning adaptive designs or comparing stopping, enrichment, or sample-size re-estimation strategies.
scientific-skills/Protocol Design/adaptive-trial-simulator/SKILL.md
Source commit 686e09dfdb45d9fa1a08664f06bb93769b3c9d91
What was checked
- Matches the observed repository HEAD
- Yes
- Scanner rules are current
- Yes
- Repository scan complete
- No
- Skill scan complete
- No
- Observed behavior
- Local scripts
- Last checked
- Nov 9, 2026
These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.
Install this skill
Choose an agent in your Stack or copy a command below. Commands fetch the pinned commit and copy only this skill directory. Existing destinations are refused. Copying a command does not install anything.
An install command is unavailable: current rules, complete repository and skill scans, an eligible behavior level and a permitted license are required.
Repository context
- Repository stars (not skill ratings)
- 2,042
- Repository last updated
- Sep 17, 2026
- License
- MIT
Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.
- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- design Derived category
Files and excerpt
File metadata and permitted, redacted excerpts come from the recorded scan. Source links are pinned to that commit.
Browse files
POLISH_CHANGELOG.mddoc · 667 bytesSKILL.mdcore · 12,070 bytesSKILL.mdcore · 12,070 bytesSKILL.mdcore · 12,070 byteseval_report_adaptive-trial-simulator_result.jsonasset · 10,858 bytesreferences/audit-reference.mddoc · 648 bytesscripts/main.pyruns · 29,278 bytes
Read excerpt
> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# Adaptive Trial Simulator
Statistical simulation platform for designing and validating adaptive clinical trial designs in silico. Enables optimization of interim analysis strategies, sample size adaptation, and early stopping rules while maintaining Type I error control.
## Quick Check
Use this command to verify that the packaged script entry point can be parsed before deeper execution.
```bash
python -m py_compile scripts/main.py
```
## Audit-Ready Commands