Menu

Individual skill

single-drug-adverse-effect-hub-first-network-pharmacology

0upvotes

Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.

awesome-med-research-skills/Protocol Design/single-drug-adverse-effect-hub-first-network-pharmacology/SKILL.md

Read pinned source

Source commit 686e09dfdb45d9fa1a08664f06bb93769b3c9d91

What was checked

Matches the observed repository HEAD
Yes
Scanner rules are current
Yes
Repository scan complete
No
Skill scan complete
Yes
Observed behavior
Instructions only
Last checked
Nov 9, 2026

These are observations at the recorded commit, not a guarantee of safety. Review the source before running it.

Install this skill

Choose an agent in your Stack or copy a command below. Commands fetch the pinned commit and copy only this skill directory. Existing destinations are refused. Copying a command does not install anything.

An install command is unavailable: current rules, complete repository and skill scans, an eligible behavior level and a permitted license are required.

Repository context

Repository stars (not skill ratings)
2,042
Repository last updated
Sep 17, 2026
License
MIT

Observed agent integration: No specific integration evidence. Standard SKILL.md installation does not imply verified compatibility.

Files and excerpt

File metadata and permitted, redacted excerpts come from the recorded scan. Source links are pinned to that commit.

Browse files
Read excerpt
> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)

# Single-Drug Adverse-Effect Hub-First Network Pharmacology Research Planner

You are an expert biomedical research planner for **single-drug adverse-effect network pharmacology**.

**Task:** Generate a **complete, structured research design** — not a literature summary,
not a generic tool list. Build a real, executable study plan with four workload options,
one recommended primary path, explicit dependency logic, a verified-reference module,
and conservative evidence labeling.

This skill is for **single-drug, single-adverse-effect network-pharmacology papers** built
around a fixed drug first, followed by adverse-effect target collection, overlap target
identification, **PPI-topology-first hub prioritization**, enrichment interpretation,
molecular docking support, and optional orthogonal validation. The core logic is:
Back to top