Individual skill
faers-multi-drug-soc-planner
Generates complete FAERS-based multi-drug single-SOC safety comparison research designs from a user-provided drug set, comparator, and adverse event domain. Always use this skill when users want to compare safety signals across multiple drugs using FAERS or OpenFDA data within one System Organ Class (SOC) or bounded AE domain. Trigger for:"FAERS study comparing drugs within one SOC", "publishable FAERS safety comparison paper", "compare neuropsychiatric adverse events across beta-blockers", "Lite/Standard/Advanced FAERS safety plans", "active-comparator restricted disproportionality", "adjusted ROR logistic regression FAERS", "within-class head-to-head drug comparison", "pharmacovigilance signal comparison", "single-SOC PT-level FAERS design", or any phrasing like "I want to compare drug X and drug Y for adverse events in FAERS" or "build a comparative pharmacovigilance paper". Always output four workload configurations (Lite / Standard / Advanced / Publication+) with a recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, and publication upgrade path.
scientific-skills/Protocol Design/faers-multi-drug-soc-planner/SKILL.md
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- Last checked
- Nov 9, 2026
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# FAERS Multi-Drug Single-SOC Safety Comparison Research Planner
Generates a complete FAERS comparative pharmacovigilance study design from a user-provided drug set, comparator logic, and target SOC. Always outputs four workload configurations and a recommended primary plan.
## Supported Study Styles
- **A. Drug Class vs Active Comparator** — e.g., beta-blockers vs ACE inhibitors for psychiatric disorders
- **B. Within-Class Head-to-Head** — e.g., propranolol vs atenolol vs metoprolol for neuropsychiatric AEs
- **C. Single-SOC + Multi-PT Deepening** — SOC-level signal + clinically meaningful PT breakdown
- **D. Active-Comparator Restricted Disproportionality** — indication-restricted confounding control
- **E. Pharmacologic-Property Heterogeneity** — lipophilic vs hydrophilic, selective vs non-selective subgroups
- **F. Sensitivity-Analysis Strengthened Design** — post hoc indication adjustment, comparator robustness
- **G. Publication-Oriented Integrated Comparative Pharmacovigilance** — full pipeline with subgroup + PT + sensitivity