Individual skill
consensus-clustering-analysis
Use when identifying stable sample subtypes from bulk expression matrices with ConsensusClusterPlus, including PAC-based model selection and consensus matrix/CDF visualization. NOT for: differential expression analysis, single-cell clustering workflows, or non-expression tables.
awesome-med-research-skills/Data Analysis/consensus-clustering-analysis/SKILL.md
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- bioinformatics Repository topic
- computational-biology Repository topic
- data-analysis Repository topic
- ai Repository topic
- biology Repository topic
- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- data Derived category
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DESCRIPTIONasset · 549 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 bytesSKILL.mdcore · 7,864 byteseval_report_consensus-clustering-analysis_result.jsonasset · 14,895 bytesreferences/algorithm.mddoc · 2,235 bytesreferences/cli-guide.mddoc · 11,363 bytesreferences/troubleshooting.mddoc · 2,960 bytesscripts/functions_analysis.Rasset · 5,709 bytesscripts/io_utils.Rasset · 2,088 bytesscripts/main.Rruns · 5,241 bytesscripts/run_analysis.Rasset · 5,901 bytesscripts/utils.Rasset · 3,697 bytesscripts/visualization.Rasset · 2,827 bytestests/data/expression_matrix.csvasset · 48,178 bytestests/data/genes.csvasset · 267 bytestests/data/groups.csvasset · 674 bytestests/run_tests.Rasset · 773 bytestests/testthat.Rasset · 889 bytestests/testthat/setup.Rasset · 251 bytestests/testthat/test-cli-smoke.Rasset · 5,658 bytestests/testthat/test-functions.Rasset · 2,178 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# Consensus Clustering Analysis
## When to Use
Use this skill when you need to identify stable sample subtypes from a bulk expression matrix with `ConsensusClusterPlus`, compare candidate clustering settings with PAC, and export consensus matrix/CDF visualizations.
Do not use this skill for differential expression analysis, single-cell clustering, or non-expression tabular data.
## When to Read External Files
| Situation | File to Read | Purpose |
|-----------|--------------|---------|
| **Need algorithm details** | `references/algorithm.md` | Consensus clustering, PAC scoring, and preprocessing assumptions |