Individual skill
diagnostic-study-quality-assessment-quadas-2
Analyzes clinical diagnostic accuracy studies for bias using the QUADAS-2 tool. Use when Claude needs to assess the quality, risk of bias, or applicability of diagnostic accuracy studies (e.g., "Assess this paper using QUADAS-2").
scientific-skills/Evidence Insight/diagnostic-study-quality-assessment-quadas-2/SKILL.md
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- Sep 17, 2026
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- bioinformatics Repository topic
- computational-biology Repository topic
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- cancer-genomics Repository topic
- data-visualization Repository topic
- differential-expression Repository topic
- genomics Repository topic
- medical Repository topic
- research Derived category
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POLISH_CHANGELOG.mddoc · 651 bytesSKILL.mdcore · 6,117 bytesSKILL.mdcore · 6,117 byteseval_report_diagnostic-study-quality-assessment-quadas-2_result.jsonasset · 8,731 bytesreferences/api_reference.mddoc · 1,024 bytesreferences/quadas_2_criteria.mddoc · 2,060 bytesscripts/pdf_extractor.pyruns · 4,123 bytesscripts/quadas_assessment.pyruns · 454 bytes
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> **Source**: [https://github.com/aipoch/medical-research-skills](https://github.com/aipoch/medical-research-skills)
# Clinical Study Bias Assessment (QUADAS-2)
This skill evaluates clinical diagnostic accuracy studies for bias and applicability concerns using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool.
## Workflow
To assess a study, follow these steps:
1. **Analyze Patient Selection**:
* Assess if the sample was consecutive or random.
* Check for case-control design (should be avoided).
* Check for inappropriate exclusions.