Individual skill
seroprevalence-surveys
Designing and analyzing seroprevalence studies — sampling, assay validation, and adjusting for test performance.
skills/seroprevalence-surveys/SKILL.md
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## Overview
seroprevalence-surveys covers population surveys measuring antibodies (or other biomarkers) to
estimate how many people have been infected or vaccinated. It focuses on the three things that
make or break serosurveys: representative sampling, validated assays, and correct statistical
adjustment for imperfect test sensitivity and specificity.
A serosurvey with a convenience sample and an unvalidated assay produces a number that is worse
than useless — it looks authoritative while being wrong.
## When to use
- Designing serosurveys: sampling frames, sample size, stratification.
- Choosing and validating serologic assays for population use.