Individual skill
deseq2-differential-expression
DESeq2 differential expression analysis skill with normalization, statistical modeling, and visualization
library/specializations/domains/science/bioinformatics/skills/deseq2-differential-expression/SKILL.md
Source commit feb68abe397acc14f32b34984975c48fedba2b33
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- Last checked
- Nov 9, 2026
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- 1,903
- Repository last updated
- Nov 1, 2026
- License
- MIT
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- transcriptomics Declared skill tag
- differential-expression Declared skill tag
- statistics Declared skill tag
- rna-seq Declared skill tag
- data Derived category
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SKILL.mdcore · 1,604 bytes
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# DESeq2 Differential Expression Skill
## Purpose
Provide DESeq2 differential expression analysis with normalization, statistical modeling, and visualization.
## Capabilities
- Size factor normalization
- Negative binomial modeling
- Shrinkage estimation
- Batch effect modeling
- Multi-factor designs
- Result visualization (MA plots, volcano plots)
## Usage Guidelines