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drug-development-guide
End-to-end drug development pipeline from target identification to regulatory...
skills/domains/pharma/drug-development-guide/SKILL.md
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# Drug Development Guide
A comprehensive skill covering the drug development pipeline from target identification through regulatory approval. Designed for pharmaceutical researchers, medicinal chemists, and clinical scientists conducting academic or industry research.
## Drug Discovery Pipeline Overview
```
Target ID -> Hit Finding -> Lead Optimization -> Preclinical -> Phase I -> Phase II -> Phase III -> Regulatory Filing
(1-2 yr) (1-2 yr) (1-3 yr) (1-2 yr) (1 yr) (2 yr) (3 yr) (1-2 yr)
Total timeline: ~10-15 years | Success rate: ~5-10% from Phase I to approval
Estimated cost: $1.3B-$2.8B per approved drug (DiMasi et al., 2016)
```