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clinicaltrials-api-v2

Search and analyze clinical trials via the ClinicalTrials.gov v2 API

skills/domains/biomedical/clinicaltrials-api-v2/SKILL.md

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# ClinicalTrials.gov v2 API Guide

## Overview

ClinicalTrials.gov is the world's largest clinical trial registry, maintained by the U.S. National Library of Medicine (NLM) at NIH. It contains over 576,000 study records from 220+ countries covering interventional trials, observational studies, and expanded access programs. The v2 API provides structured JSON access with field-level filtering, cursor-based pagination, and statistics endpoints.

Key v2 improvements over the legacy API: JSON-native responses, sparse field selection via the `fields` parameter, `nextPageToken` pagination, and dedicated statistics endpoints. Study data is organized into `protocolSection` (sponsor-submitted) and `derivedSection` (NLM-computed).

## Authentication

No authentication required. All endpoints are publicly accessible without API keys or registration. Users should comply with NCBI usage policies and maintain reasonable request rates.

## Core Endpoints