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reactome-database

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

backend/cli/skills/databases/reactome-database/SKILL.md

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# Reactome Database

## Overview

Reactome is a free, open-source, curated pathway database with 2,825+ human pathways. Query biological pathways, perform overrepresentation and expression analysis, map genes to pathways, explore molecular interactions via REST API and Python client for systems biology research.

## When to Use This Skill

This skill should be used when:
- Performing pathway enrichment analysis on gene or protein lists
- Analyzing gene expression data to identify relevant biological pathways
- Querying specific pathway information, reactions, or molecular interactions
- Mapping genes or proteins to biological pathways and processes
- Exploring disease-related pathways and mechanisms