Individual skill

clinical-trial-ipd-sim

End-to-end R workflow to simulate individual patient data (IPD) for a registered clinical trial using a g-formula causal-DAG simulator. Given an NCT ID with posted results and a protocol PDF, derives CRFs, builds an evidence-based causal DAG, parameterizes structural equations from ClinicalTrials.gov / literature priors, runs an R6 forward simulator, and calibrates marginal statistics to the published results without breaking causal identifiability. Emits CSV CRFs, a validated CDISC ODM v2.0 export, and an interactive DAG page.

clinical-trial-ipd-sim/SKILL.md

Source commit e5db96d54ef5a79cbfd06e2339a3351e4583f8da

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Observed behavior

Network or broad shell

Last checked

Nov 4, 2026

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