Individual skill
evo-protein-expression-analysis
Use when populating Excel workbooks for quantitative proteomics tasks - computing expression lookups, group statistics, and log2 fold-change values using Python and writing numeric results via openpyxl while preserving cell formatting. Handles two-sheet workbooks (Task + Data) with 2D protein×sample expression matrices.
tasks-evolved/protein-expression-analysis/environment/skills/evo-protein-expression-analysis/SKILL.md
Source commit 84ca182da055fafb6453dcec4a6defdbbfd987c1
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- Local scripts
- Last checked
- Nov 6, 2026
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- Repository last updated
- Sep 10, 2026
- License
- Apache-2.0
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- agent-skills Repository topic
- ai-agents Repository topic
- llm-agents Repository topic
- open-world Repository topic
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# evo-protein-expression-analysis
Utilities for populating Excel workbooks with proteomics expression values,
group statistics, and fold-change calculations while preserving all cell formatting.
## CRITICAL: Write computed numeric values, NOT formulas
openpyxl does NOT have a calculation engine. If you write Excel formulas (strings
starting with `=`), they will only be evaluated when the file is opened in Excel.
Tools that read the file with `data_only=True` will see `None` for all formula cells.
**You MUST compute values in Python and write float/int results directly.**
## Key facts about the protein_expression.xlsx task