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solublempnn
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# SolubleMPNN Solubility-Optimized Sequence Design
ProteinMPNN variant trained to design sequences with higher solubility in aqueous solution. Reduces aggregation propensity and improves expression yields in E. coli and cell-free systems.
## Installation
```bash
git clone https://github.com/dauparas/LigandMPNN
cd LigandMPNN
pip install -e .
bash get_model_params.sh
```
## When to Use SolubleMPNN vs ProteinMPNN
